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The use of computer-assisted-telephone-interviewing to diagnose seizures, epilepsy and Idiopathic Generalized Epilepsy


D'Souza, WJ and Stankovich, J and O'Brien, TJ and Bower, S and Pearce, N and Cook, MJ, The use of computer-assisted-telephone-interviewing to diagnose seizures, epilepsy and Idiopathic Generalized Epilepsy, Epilepsy Research, 91, (1) pp. 20-27. ISSN 0920-1211 (2010) [Refereed Article]

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DOI: doi:10.1016/j.eplepsyres.2010.06.003


Background: Computer-assisted-telephone-interviewing (CATI), widely used in market research, could be a useful alternative for conducting diagnostic interviews in epilepsy epidemiology. Methods: We administered a diagnostic seizure questionnaire by CATI, interpreting the responses with standardized classification guidelines, compared against an epilepsy specialist’s assessment, for agreement [Kappa statistic (!)], sensitivity, specificity, positive predictive value, negative predictive value and Youden’s Index (YI). Results: 99 outpatients with 382 lifetime events participated: 22 generalized-onset epilepsy [16 Idiopathic Generalized Epilepsy (IGE)], 59 partial-onset epilepsy, 12 non-epileptic and 6 uncertain. We observed almost perfect agreement in diagnosing epilepsy (! = 0.94), seizure-onset types (! = 0.84), simple or complex partial seizures (! = 0.87), any generalized non-convulsive seizure (! = 0.82), and IGE (! = 0.82). Although substantial, agreement was not as close for secondarily generalized seizures (! = 0.74), and generalized tonic-clonic seizures (! = 0.79). This related more to under-recognition of individual generalized non-convulsive seizures rather than misinterpretation of partial seizures.

Item Details

Item Type:Refereed Article
Keywords:Epilepsy; Epidemiology; Questionnaires; Diagnosis; Validation
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Neurology and neuromuscular diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:D'Souza, WJ (Mr Wendyl D'Souza)
UTAS Author:Stankovich, J (Dr Jim Stankovich)
ID Code:66079
Year Published:2010
Web of Science® Times Cited:18
Deposited By:Menzies Institute for Medical Research
Deposited On:2010-12-20
Last Modified:2011-05-02

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