Holland, DJ and Sharman, JE and Leano, RL and Marwick, TH, Gender differences in systolic tissue velocity: role of left ventricular length, European Journal of Echocardiography, 10, (8) pp. 941-946. ISSN 1525-2167 (2009) [Refereed Article]
Copyright 2009 The Author
Methods and results LV tissue velocities were measured in 71 controls and 222 patients with T2DM by pulsed-wave Doppler and colour-coded tissue Doppler (TDI) during systole (S’ and Sm) and diastole (early, E’ and Em, and late, A’ and Am) at the basal septum and lateral wall. Both systolic tissue velocities were higher in males than in females within controls (S’: 7.3±1.2 vs. 6.6±1.0 cm/s; P = 0.017, Sm: 6.2±1.0 vs. 5.5±0.7 cm/s; P = 0.002) but only by colour-coded TDI in patients with T2DM (Sm: 5.7±1.7 vs. 4.9±1.7 cm/s; P = 0.025). Correction for LV length negated the difference between genders in the controls and patients with T2DM (P > 0.05 for all). In controls, LV length was the strongest predictor of S’ (β = 0.393, P = 0.002), whereas height was the strongest predictor of Sm (β = 0.394, P = 0.003).
Conclusion In controls, systolic tissue velocities are significantly higher in males compared with females, which may be explained by the increased chamber size of men.
|Item Type:||Refereed Article|
|Research Division:||Medical and Health Sciences|
|Research Group:||Cardiorespiratory Medicine and Haematology|
|Research Field:||Cardiology (incl. Cardiovascular Diseases)|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cardiovascular System and Diseases|
|Author:||Sharman, JE (Professor James Sharman)|
|Author:||Marwick, TH (Professor Tom Marwick)|
|Web of Science® Times Cited:||2|
|Deposited By:||Menzies Institute for Medical Research|
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