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Gender differences in systolic tissue velocity: role of left ventricular length


Holland, DJ and Sharman, JE and Leano, RL and Marwick, TH, Gender differences in systolic tissue velocity: role of left ventricular length, European Journal of Echocardiography, 10, (8) pp. 941-946. ISSN 1525-2167 (2009) [Refereed Article]

Copyright Statement

Copyright 2009 The Author

DOI: doi:10.1093/ejechocard/jep103


Aims Previous research has described differences in left ventricular (LV) systolic tissue velocity between genders. This study aimed to determine the association between LV tissue velocity and LV size in healthy controls and in those with type 2 diabetes (T2DM).
Methods and results LV tissue velocities were measured in 71 controls and 222 patients with T2DM by pulsed-wave Doppler and colour-coded tissue Doppler (TDI) during systole (S and Sm) and diastole (early, E and Em, and late, A and Am) at the basal septum and lateral wall. Both systolic tissue velocities were higher in males than in females within controls (S: 7.31.2 vs. 6.61.0 cm/s; P = 0.017, Sm: 6.21.0 vs. 5.50.7 cm/s; P = 0.002) but only by colour-coded TDI in patients with T2DM (Sm: 5.71.7 vs. 4.91.7 cm/s; P = 0.025). Correction for LV length negated the difference between genders in the controls and patients with T2DM (P > 0.05 for all). In controls, LV length was the strongest predictor of S (β = 0.393, P = 0.002), whereas height was the strongest predictor of Sm (β = 0.394, P = 0.003).
Conclusion In controls, systolic tissue velocities are significantly higher in males compared with females, which may be explained by the increased chamber size of men.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Sharman, JE (Professor James Sharman)
UTAS Author:Marwick, TH (Professor Tom Marwick)
ID Code:63747
Year Published:2009
Web of Science® Times Cited:3
Deposited By:Menzies Institute for Medical Research
Deposited On:2010-05-26
Last Modified:2014-05-28

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