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Extracranial metastases of a glioblastoma multiforme to the pleura, small bowel and pancreas


Mujic, A and Hunn, AWM and Taylor, BV and Lowenthal, RM, Extracranial metastases of a glioblastoma multiforme to the pleura, small bowel and pancreas, Journal of Clinical Neuroscience, 13, (6) pp. 677-681. ISSN 0967-5868 (2006) [Refereed Article]

DOI: doi:10.1016/j.jocn.2005.08.016


Extracranial metastases of glioblastoma multiforme (GBM) are rare and usually occur in the context of recurrent intracranial GBM. We present a 39-year-old man with histologically confirmed GBM. The patient remained well for nearly 2 years, with no signs of recurrent tumour. He then presented with distant recurrence within the brain at the same time as developing pneumonia and epigastric pain. A computed tomography scan of the patient's abdomen and chest showed several intra-abdominal masses, including one in the head of the pancreas as well as a separate mass at the base of the left lung. A computed tomography-guided biopsy of the pancreatic mass demonstrated histological appearances identical to those of the original GBM. This unusual case raises the possibility of a link between prolonged survival with GBM and the occurrence of extracranial disease.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Central nervous system
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Taylor, BV (Professor Bruce Taylor)
ID Code:63396
Year Published:2006
Web of Science® Times Cited:27
Deposited By:Menzies Institute for Medical Research
Deposited On:2010-05-05
Last Modified:2010-06-18

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