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Extracranial metastases of a glioblastoma multiforme to the pleura, small bowel and pancreas

journal contribution
posted on 2023-05-17, 02:30 authored by Mujic, A, Hunn, AWM, Bruce TaylorBruce Taylor, Lowenthal, RM
Extracranial metastases of glioblastoma multiforme (GBM) are rare and usually occur in the context of recurrent intracranial GBM. We present a 39-year-old man with histologically confirmed GBM. The patient remained well for nearly 2 years, with no signs of recurrent tumour. He then presented with distant recurrence within the brain at the same time as developing pneumonia and epigastric pain. A computed tomography scan of the patient's abdomen and chest showed several intra-abdominal masses, including one in the head of the pancreas as well as a separate mass at the base of the left lung. A computed tomography-guided biopsy of the pancreatic mass demonstrated histological appearances identical to those of the original GBM. This unusual case raises the possibility of a link between prolonged survival with GBM and the occurrence of extracranial disease.

History

Publication title

Journal of Clinical Neuroscience

Volume

13

Issue

6

Pagination

677-681

ISSN

0967-5868

Department/School

Menzies Institute for Medical Research

Publisher

Churchill Livingstone

Place of publication

1-3 Baxters Place, Leith Walk, Edinburgh, Scotland, Midlothian, Eh1 3Af

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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