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A novel exploratory method for visual recombination detection

Citation

Strimmer, K and Forslund, K and Holland, BR and Moulton, V, A novel exploratory method for visual recombination detection, Genome Biology, 4, (5) pp. R33. ISSN 1465-6914 (2003) [Refereed Article]


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Copyright Statement

© 2003 Strimmer et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL

Official URL: http://genomebiology.com/2003/4/5/R33

DOI: doi:10.1186/gb-2003-4-5-r338976

Abstract

A versatile visual approach for detecting recombination and identifying recombination breakpoints within a sequence alignment is presented. The method is based on two novel diagrams - the highway plot and the occupancy plot - that graphically portray phylogenetic inhomogeneity along an alignment, and can be viewed as a synthesis of two widely used but unrelated methods: bootscanning and quartet-mapping. To illustrate the method, simulated data and HIV-1 and influenza A datasets are investigated.

Item Details

Item Type:Refereed Article
Research Division:Information and Computing Sciences
Research Group:Computer Software
Research Field:Bioinformatics Software
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Mathematical Sciences
Author:Holland, BR (Associate Professor Barbara Holland)
ID Code:63087
Year Published:2003
Web of Science® Times Cited:13
Deposited By:Mathematics
Deposited On:2010-04-14
Last Modified:2011-10-06
Downloads:265 View Download Statistics

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