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Increase in Quality, but Not Quantity, of Clinical Trials in Acute Pain: 1992 Versus 2007
journal contribution
posted on 2023-05-22, 01:52 authored by Reeves, MDThe annual number of published clinical trials in acute postoperative pain in adults has changed little in 15 yr and, as a fraction of all clinical trials published in the six highest impact journals in anesthesiology, has actually decreased from 16% (95% confidence interval: 12-20) to 11% (95% confidence interval: 9-15). However, the methodological quality of reports has improved, with explicit statements on power analysis, allocation concealment, and specification of primary end points exceeding 90% of reports in 2007. There has been a shift in hypothesis interests away from neuraxial analgesia and toward multimodal analgesia.
History
Publication title
Anesthesia and AnalgesiaVolume
109Issue
5Pagination
1656-1658ISSN
0003-2999Department/School
Tasmanian School of MedicinePublisher
Lippincott Williams & WilkinsPlace of publication
530 Walnut St, Philadelphia, USA, Pa, 19106-3621Rights statement
© 2009 by International Anesthesia Research Society.Repository Status
- Restricted