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Increase in Quality, but Not Quantity, of Clinical Trials in Acute Pain: 1992 Versus 2007

Citation

Reeves, MD, Increase in Quality, but Not Quantity, of Clinical Trials in Acute Pain: 1992 Versus 2007 , Anesthesia and Analgesia, 109, (5) pp. 1656-1658. ISSN 0003-2999 (2009) [Contribution to Refereed Journal]


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Copyright Statement

© 2009 by International Anesthesia Research Society.

Official URL: http://www.anesthesia-analgesia.org/

DOI: doi:10.1213/ANE.0b013e3181b626b6

Abstract

The annual number of published clinical trials in acute postoperative pain in adults has changed little in 15 yr and, as a fraction of all clinical trials published in the six highest impact journals in anesthesiology, has actually decreased from 16% (95% confidence interval: 12-20) to 11% (95% confidence interval: 9-15). However, the methodological quality of reports has improved, with explicit statements on power analysis, allocation concealment, and specification of primary end points exceeding 90% of reports in 2007. There has been a shift in hypothesis interests away from neuraxial analgesia and toward multimodal analgesia.

Item Details

Item Type:Contribution to Refereed Journal
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Anaesthesiology
Objective Division:Health
Objective Group:Other Health
Objective Field:Health not elsewhere classified
Author:Reeves, MD (Dr Mark Reeves)
ID Code:62664
Year Published:2009
Web of Science® Times Cited:4
Deposited By:Rural Clinical School
Deposited On:2010-03-16
Last Modified:2010-06-28
Downloads:0

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