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Management of cow's milk protein allergy in infants and young children: An expert panel perspective


Allen, KJ and Davidson, GP and Day, AS and Hill, DJ and Kemp, AS and Peake, JE and Prescott, SL and Shugg, AW and Sinn, JKH and Heine, RG, Management of cow's milk protein allergy in infants and young children: An expert panel perspective, Journal of Paediatrics and Child Health, 45, (9) pp. 481-486. ISSN 1034-4810 (2009) [Refereed Article]

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DOI: doi:10.1111/j.1440-1754.2009.01546.x


Cow’s milk protein allergy is a condition commonly managed by general practitioners and paediatricians. The diagnosis is usually made in the first 12 months of life. Management of immediate allergic reactions and anaphylaxis includes the prevention of accidental food ingestion and provision of an adrenaline autoinjector, if appropriate. By contrast, the clinical course of delayed food-allergic manifestations is characterised by chronicity, and is often associated with nutritional or behavioural sequelae. Correct diagnosis of these non-IgE-mediated conditions may be delayed due to a lack of reliable diagnostic markers. This review aims to guide clinicians in the: (i) diagnostic evaluation (skin prick testing or measurement of food-specific serum IgE levels; indications for diagnostic challenges for suspected IgE- and non-IgE-mediated food allergy), (ii) dietary treatment, (iii) assessment of response to treatment, (iv) differential diagnosis and further diagnostic work-up in non-responders, (v) follow-up assessment of tolerance development and (vi) recommendations for further referral.

Item Details

Item Type:Refereed Article
Keywords:anaphylaxis; eosinophilic oesophagitis; food challenge; gastrointestinal; hypoallergenic formula; skin prick test.
Research Division:Biomedical and Clinical Sciences
Research Group:Immunology
Research Field:Allergy
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Shugg, AW (Dr Albert Shugg)
ID Code:62232
Year Published:2009
Web of Science® Times Cited:53
Deposited By:Rural Clinical School
Deposited On:2010-03-10
Last Modified:2012-02-20

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