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Alois Alzheimer and Alzheimer's disease: a centennial perspective

Citation

Small, DH and Cappai, R, Alois Alzheimer and Alzheimer's disease: a centennial perspective, Journal of Neurochemistry, 99, (3) pp. 708-710. ISSN 0022-3042 (2006) [Refereed Article]


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DOI: doi:10.1111/j.1471-4159.2006.04212.x

Abstract

The year 2006 is the centenary of the famous presentation of Alois Alzheimer which first described the neuropathology of Alzheimer's disease (AD). Since this presentation, enormous progress has been made in understanding the biology of AD. The central role of the -amyloid protein (A) in the pathogenesis of AD and the relationship between plaque and tangle pathology is now much better understood. In this article, we review the current status of the amyloid hypothesis of AD and its role in the development of future therapy.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Neurosciences
Research Field:Neurosciences not elsewhere classified
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Neurodegenerative Disorders Related to Ageing
Author:Small, DH (Professor David Small)
ID Code:61441
Year Published:2006
Web of Science® Times Cited:39
Deposited By:Menzies Institute for Medical Research
Deposited On:2010-03-03
Last Modified:2010-07-13
Downloads:0

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