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Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

journal contribution
posted on 2023-05-17, 01:14 authored by Bahlo, M, Booth, DR, Broadley, SA, Brown, MA, Simon James FooteSimon James Foote, Griffiths, LR, Kilpatrick, TJ, Lechner-Scott, J, Moscato, P, Perreau, VM, Rubio, JP, Scott, RJ, Jim Stankovich, Stewart, GJ, Bruce TaylorBruce Taylor, Wiley, J, Clarke, G, Cox, MB, Csurhes, PA, Danoy, P, Drysdale, KE, Field, J, Greer, JM, Mayura Guru, P, Hadler, J, McMorran, BJ, Jensen, CJ, Johnson, LJ, McCallum, R, Merriman, M, Merriman, T, Pryce, K, Tajouri, L, Wilkins, EJ, Browning, BL, Browning, SR, Perera, DI, Butzkueven, H, Carroll, WM, Chapman, C, Kermode, AG, Marriott, M, Mason, D, Heard, RN, Pender, MP, Slee, M, Tubridy, N, Willoughby, E
To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413 controls. We performed replication in an independent set of 2,256 cases and 2,310 controls, for a total of 3,874 cases and 5,723 controls.

History

Publication title

Nature Genetics

Volume

41

Issue

7

Pagination

824-830

ISSN

1061-4036

Department/School

Menzies Institute for Medical Research

Publisher

Nature Publishing Group

Place of publication

345 Park Ave South, New York, USA, Ny, 10010-1707

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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