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Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

Citation

Bahlo, M and Booth, DR and Broadley, SA and Brown, MA and Foote, SJ and Griffiths, LR and Kilpatrick, TJ and Lechner-Scott, J and Moscato, P and Perreau, VM and Rubio, JP and Scott, RJ and Stankovich, J and Stewart, GJ and Taylor, BVM and Wiley, J and Clarke, G and Cox, MB and Csurhes, PA and Danoy, P and Drysdale, KE and Field, J and Greer, JM and Mayura Guru, P and Hadler, J and McMorran, BJ and Jensen, CJ and Johnson, LJ and McCallum, R and Merriman, M and Merriman, T and Pryce, K and Tajouri, L and Wilkins, EJ and Browning, BL and Browning, SR and Perera, DI and Butzkueven, H and Carroll, WM and Chapman, C and Kermode, AG and Marriott, M and Mason, D and Heard, RN and Pender, MP and Slee, M and Tubridy, N and Willoughby, E, Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20, Nature Genetics, 41, (7) pp. 824-830. ISSN 1061-4036 (2009) [Refereed Article]

DOI: doi:10.1038/ng.396

Abstract

To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413 controls. We performed replication in an independent set of 2,256 cases and 2,310 controls, for a total of 3,874 cases and 5,723 controls.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Neurosciences
Research Field:Central Nervous System
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Nervous System and Disorders
Author:Foote, SJ (Professor Simon Foote)
Author:Stankovich, J (Dr Jim Stankovich)
Author:Taylor, BVM (Professor Bruce Taylor)
Author:Drysdale, KE (Ms Karen Drysdale)
Author:Mayura Guru, P (Mrs Preethi Mayura Guru)
Author:McMorran, BJ (Dr Brendan McMorran)
Author:Perera, DI (Miss Devindri Perera)
ID Code:60455
Year Published:2009
Web of Science® Times Cited:308
Deposited By:Menzies Institute for Medical Research
Deposited On:2010-02-05
Last Modified:2011-08-24
Downloads:0

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