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Clopidogrel prescribing and concordance with the Pharmaceutical Benefits Scheme in hospital patients


Luinstra, M and Naunton, M and Peterson, GM and Bereznicki, LRE, Clopidogrel prescribing and concordance with the Pharmaceutical Benefits Scheme in hospital patients, Journal of Pharmacy Practice and Research , 39, (4) pp. 265-268. ISSN 1445-937X (2009) [Refereed Article]

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Copyrights 2009 The Society of Hospital Pharmacists of Australia

DOI: doi:10.1002/j.2055-2335.2009.tb00471.x


Background: Clopidogrel is used for the secondary prevention of cerebrovascular and cardiovascular events. Clopidogrel has a similar safety profile to low-dose aspirin but is considerably more expensive. Clopidogrel is subsidised for restricted indications via the Pharmaceutical Benefits Scheme (PBS). Aim: To examine c1opidogrel prescribing in hospital; and to identify patients discharged on clopidogrel according to PBS criteria. Method: Cross-sectional evaluation of patients started on clopidogrel (July 2006 to June 2007) at the Royal Darwin and Royal Hobart Hospitals.Clopidogrel prescribing was examined and the indication for discharge on c1opidogrel was documented. The primary outcome was concordance between clopidogrel use and PBS criteria. Results: Data were collected for 385 patients. 54% of patients from the Royal Darwin Hospital and 39% of patients from the Royal Hobart Hospital discharged on c1opidogrel met PBS criteria.The main reason for noncompliance with the PBS was absenceof a history of cardiovascularor cerebrovascularevents while on low-dose aspirin and an absence of contraindications to aspirin at the time of c1opidogrel prescribing. Conclusion: Although c1opidogrel prescribing at the hospitals was often not in accordance with PBS criteria, in most cases prescribing was based on the available evidence.

Item Details

Item Type:Refereed Article
Keywords:clopidogrel, prevention, cardiovascular, data, research, hospital patients, Pharmaceutical Benefits Scheme
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacology and therapeutics
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Luinstra, M (Ms Marianne Luinstra)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
UTAS Author:Bereznicki, LRE (Professor Luke Bereznicki)
ID Code:60281
Year Published:2009
Deposited By:Pharmacy
Deposited On:2010-01-28
Last Modified:2010-06-16
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