eCite Digital Repository

Cell-surface carbohydrate antigen(s) of wild-type Neoparamoeba spp are immunodominant in sea-cage cultured Atlantic salmon (Salmo salar L) affected by amebic gill disease (AGD)

Citation

Vincent, BN and Adams, MB and Nowak, BF and Morrison, RN, Cell-surface carbohydrate antigen(s) of wild-type Neoparamoeba spp are immunodominant in sea-cage cultured Atlantic salmon (Salmo salar L) affected by amebic gill disease (AGD), Aquaculture, 288, (3-4) pp. 153-158. ISSN 0044-8486 (2009) [Refereed Article]

DOI: doi:10.1016/j.aquaculture.2008.11.036

Abstract

A proportion of Atlantic salmon experimentally affected by amoebic gill disease (AGD) develop a serum antibody response to wild-type Neoparamoeba spp.. These antibodies bind cell-surface epitope(s) and in most cases the epitope(s) are sensitive to sodium periodate oxidation. In this study, blood was obtained from triploid and diploid sea-farmed Atlantic salmon after 8, 10 and 13 months of sea-cage culture. An additional group of Atlantic salmon broodstock was sampled at 15 months after transfer to sea. Anti-Neoparamoeba spp. (anti-NP) antibodies that bound cell-surface carbohydrate antigens of wild-type Neoparamoeba spp. were detected in several of these samples. In all cases, the presence of plasma anti-NP antibodies does not appear to be associated with the level of AGD-like gross gill pathology. These results provide further evidence for the development of an antibody response in AGD-affected Atlantic salmon and that carbohydrate epitopes of wild-type Neoparamoeba spp. are immunodominant.

Item Details

Item Type:Refereed Article
Research Division:Agricultural and Veterinary Sciences
Research Group:Fisheries Sciences
Research Field:Fish Pests and Diseases
Objective Division:Animal Production and Animal Primary Products
Objective Group:Fisheries - Aquaculture
Objective Field:Aquaculture Fin Fish (excl. Tuna)
Author:Vincent, BN (Miss Benita Vincent)
Author:Adams, MB (Dr Mark Adams)
Author:Nowak, BF (Professor Barbara Nowak)
Author:Morrison, RN (Dr Richard Morrison)
ID Code:60139
Year Published:2009
Web of Science® Times Cited:9
Deposited By:NC Marine Conservation and Resource Sustainability
Deposited On:2010-01-15
Last Modified:2011-09-20
Downloads:0

Repository Staff Only: item control page