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Experimental vaccination of Atlantic salmon (Salmo salar L) against marine flexibacteriosis

Citation

van Gelderen, R and Carson, J and Nowak, BF, Experimental vaccination of Atlantic salmon (Salmo salar L) against marine flexibacteriosis, Aquaculture, 288, (1-2) pp. 7-13. ISSN 0044-8486 (2009) [Refereed Article]

DOI: doi:10.1016/j.aquaculture.2008.11.012

Abstract

Tenacibaculum maritimum infections can cause losses in mariculture, however there is no commercially available vaccine in Australia. A vaccination trial was undertaken using 4 groups: Control, IP Control, Vaccine, and Vaccine + Adjuvant. Within the challenge period of 27 days, significant protection was demonstrated in fish injected with the Vaccine + Adjuvant compared to all other groups. RPS values were calculated at 79.6% and 78.0%. Fish vaccinated without adjuvant did show lower mortalities than unvaccinated fish, however, it was not significantly different from both unvaccinated groups. Low RPS values at 27.7% and 22.0% indicate that the vaccine without adjuvant could not provide sufficient protection from a moderate challenge of T. maritimum. Side effects of the oil based adjuvant, Freund's incomplete adjuvant (FIA) were noted. All fish injected with the Vaccine + Adjuvant had black/brown pigment associated with the external surface of the fundic region of the stomach. Histological examination revealed this material to be black/brown pigmentation most likely caused by melanin. An inflammatory response was noted around this material with the formations of granulomas and cysts. 2008 Elsevier B.V. All rights reserved

Item Details

Item Type:Refereed Article
Research Division:Agricultural and Veterinary Sciences
Research Group:Fisheries Sciences
Research Field:Fish Pests and Diseases
Objective Division:Animal Production and Animal Primary Products
Objective Group:Fisheries - Aquaculture
Objective Field:Aquaculture Fin Fish (excl. Tuna)
Author:van Gelderen, R (Ms Rebecca van Gelderen)
Author:Carson, J (Dr Jeremy Carson)
Author:Nowak, BF (Professor Barbara Nowak)
ID Code:60128
Year Published:2009
Web of Science® Times Cited:9
Deposited By:NC Marine Conservation and Resource Sustainability
Deposited On:2010-01-15
Last Modified:2011-09-20
Downloads:0

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