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Asymmetric Cyclopropanation of Olefins with an in situ Generated


Muller, P and Ghanem, A, Asymmetric Cyclopropanation of Olefins with an in situ Generated, Synlett, 2003, (12) pp. 1830-1833. ISSN 1437-2096 (2003) [Refereed Article]

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© Georg Thieme Verlag 2003

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DOI: doi:10.1055/s-2003-41456


A procedure for the in situ generation of the phenyliodonium ylide (2) derived from Meldrum's acid (1) and its Rh(II)-catalyze­d decomposition to afford an intermediate metallocarbene is described. In the presence of olefins, cyclopropanes are formed with yields and enantioselectivity comparable to that resulting from cyclopropanation with the isolated ylide 2.

Item Details

Item Type:Refereed Article
Keywords:asymmetric catalysis - alkenes - carbenes - rhodium - ylides
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Ghanem, A (Dr Ashraf Ghanem)
ID Code:58419
Year Published:2003
Web of Science® Times Cited:25
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2009-10-02
Last Modified:2009-10-06

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