Management dilemma; a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma: a case report
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Lees, AN and Reid, DW, Management dilemma; a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma: a case report, Journal of Medical Case Report, 2, (Dec 15) pp. 1-3. ISSN 1752-1947 (2008) [Professional, Non Refereed Article]
Introduction: There are increasing reports of bowel cancer in cystic fibrosis, suggesting a possible causal link. Individuals with cystic fibrosis who have advanced lung disease present a high operative risk, limiting curative treatment options in early bowel malignancy. Case presentation: We describe a 41-year-old Caucasian woman with cystic fibrosis and severe lung disease who had been considered for lung transplantation, who presented with rectal bleeding and was found to have a Stage I adenocarcinoma of the sigmoid colon. After considerable discussion as to the operative risks, she underwent a laparoscopic resection and remains relatively well 1 year postoperatively with no recurrence. Conclusion: We discuss the complexity of the management decisions for cystic fibrosis patients with severe lung disease and early stage colonic malignancy, particularly in the context of potential need for lung transplantation. The case demonstrates that cystic fibrosis patients with very severe lung function impairment may undergo laparoscopic abdominal surgical interventions without compromising postoperative airway clearance. © 2008 Lees and Reid; licensee BioMed Central Ltd.
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