eCite Digital Repository

A mechanistic study on the oxidation of hydrazides: application to the tuberculosis drug isoniazid

Citation

Amos, RIJ and Gourlay, BS and Schiesser, CH and Smith, Jason and Yates, BF, A mechanistic study on the oxidation of hydrazides: application to the tuberculosis drug isoniazid, Chemical Communications, 2008, (14) pp. 1695-1697. ISSN 1359-7345 (2008) [Refereed Article]

Copyright Statement

Copyright 2008 The Royal Society of Chemistry

DOI: doi:10.1039/b719570b

Abstract

Herein we report radical trapping experiments that support the formation of an acyl radical as the active species from the oxidation of isoniazid; these data provide insight into the mechanism of hydrazide oxidation. The Royal Society of Chemistry.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Organic Chemistry
Research Field:Physical Organic Chemistry
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Amos, RIJ (Dr Ruth Amos)
Author:Gourlay, BS (Dr Brendon Gourlay)
Author:Smith, Jason (Associate Professor Jason Smith)
Author:Yates, BF (Professor Brian Yates)
ID Code:55265
Year Published:2008
Web of Science® Times Cited:22
Deposited By:Chemistry
Deposited On:2009-03-08
Last Modified:2015-11-04
Downloads:0

Repository Staff Only: item control page