eCite Digital Repository
A mechanistic study on the oxidation of hydrazides: application to the tuberculosis drug isoniazid
Citation
Amos, RIJ and Gourlay, BS and Schiesser, CH and Smith, Jason and Yates, BF, A mechanistic study on the oxidation of hydrazides: application to the tuberculosis drug isoniazid, Chemical Communications, 2008, (14) pp. 1695-1697. ISSN 1359-7345 (2008) [Refereed Article]
Copyright Statement
Copyright 2008 The Royal Society of Chemistry
DOI: doi:10.1039/b719570b
Abstract
Herein we report radical trapping experiments that support the formation of an acyl radical as the active species from the oxidation of isoniazid; these data provide insight into the mechanism of hydrazide oxidation. © The Royal Society of Chemistry.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Research Division: | Chemical Sciences |
| Research Group: | Organic chemistry |
| Research Field: | Physical organic chemistry |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding knowledge |
| Objective Field: | Expanding knowledge in the chemical sciences |
| UTAS Author: | Amos, RIJ (Dr Ruth Amos) |
| UTAS Author: | Gourlay, BS (Dr Brendon Gourlay) |
| UTAS Author: | Smith, Jason (Professor Jason Smith) |
| UTAS Author: | Yates, BF (Professor Brian Yates) |
| ID Code: | 55265 |
| Year Published: | 2008 |
| Web of Science® Times Cited: | 36 |
| Deposited By: | Chemistry |
| Deposited On: | 2009-03-08 |
| Last Modified: | 2015-11-04 |
| Downloads: | 0 |
Repository Staff Only: item control page