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Microfluidic devices for flow-through supported palladium catalysis on porous organic monolith
journal contribution
posted on 2023-05-16, 23:03 authored by Allan CantyAllan Canty, Deverell, JA, Anissa GoemannAnissa Goemann, Rosanne Guijt, Thomas RodemannThomas Rodemann, Jason SmithJason SmithFlow-through microreactors are described, constructed of fused silica capillaries with an internal diameter of 100μm and glass microchips with a channel dimension of 150μm and involving the in situ UV-initiated synthesis of a poly(glycidyl methacrylate-co-ethylene dimethacrylate) porous polymer monolith. The monolith is a continuous material covalently bonded to the capillary or chip walls, with good flow-through properties. Epoxide ring-opening through amine attack by 5-amino-1,10-phenanthroline and coordination to dichloropalladium(ii) allows use of the microreactors for Suzuki–Miyaura catalysis. The long-term stability and reliability of the robust lab on a chip microreactor is demonstrated by operation for 96 h, exhibiting undiminished reactivity, and very low leaching of palladium.
History
Publication title
Australian Journal of ChemistryVolume
61Issue
8Pagination
630-633ISSN
0004-9425Department/School
School of Natural SciencesPublisher
CSIRO PublishingPlace of publication
MelbourneRights statement
© CSIRO 2008Repository Status
- Restricted