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Decline in Physical Fitness From Childhood to Adulthood Associated With Increased Obesity and Insulin Resistance in Adults


Dwyer, T and Magnussen, CG and Schmidt, MD and Ukoumunne, OC and Ponsonby, AL and Raitakari, OT and Zimmet, PZ and Blair, SN and Thomson, Russell and Cleland, V and Venn, A, Decline in Physical Fitness From Childhood to Adulthood Associated With Increased Obesity and Insulin Resistance in Adults , Diabetes Care, 32, (4) pp. 683-687 . ISSN 0149-5992 (2008) [Refereed Article]

DOI: doi:10.2337/dc08-1638


OBJECTIVE - To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance. RESEARCH DESIGN AND METHODS - A prospective cohort study set in Australia in 2004-2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI≥ 30 kg/m2, respectively. RESULTS - Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6-5.6]) and insulin resistance (1.7 [1.1-2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6-7.7]) and insulin resistance (2.1 [1.5-2.9]) per unit decline. CONCLUSIONS - A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults. © 2009 by the American Diabetes Association.

Item Details

Item Type:Refereed Article
Research Division:Health Sciences
Research Group:Epidemiology
Research Field:Epidemiology not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Dwyer, T (Professor Terry Dwyer)
UTAS Author:Magnussen, CG (Associate Professor Costan Magnussen)
UTAS Author:Schmidt, MD (Dr Michael Schmidt)
UTAS Author:Ponsonby, AL (Professor Anne Ponsonby)
UTAS Author:Thomson, Russell (Dr Russell Thomson)
UTAS Author:Cleland, V (Associate Professor Verity Cleland)
UTAS Author:Venn, A (Professor Alison Venn)
ID Code:53855
Year Published:2008
Web of Science® Times Cited:91
Deposited By:Menzies Institute for Medical Research
Deposited On:2009-01-14
Last Modified:2011-08-25

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