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N-acylhomoserine lactone-mediated quorum sensing: a twist in the tail and a blow for host immunity
Citation
Cooley, MA and Chhabra, SR and Williams, P, N-acylhomoserine lactone-mediated quorum sensing: a twist in the tail and a blow for host immunity, Chemistry & Biology, 15, (11) pp. 1141-1147. ISSN 1074-5521 (2008) [Contribution to Refereed Journal]
DOI: doi:10.1016/j.chembiol.2008.10.010
Abstract
Communication through quorum sensing (QS) enables bacterial populations to coordinate their behavior. Recent work on N-acylhomoserine lactone-mediated QS has revealed that some soil bacteria exploit host-derived substrates to generate an alternative N-substituted homoserine lactone. New light has also been shed on the mechanism by which N-(3-oxo-dodecanoyl)-l-homoserine lactone modulates host inflammatory signaling pathways to promote bacterial survival. © 2008 Elsevier Ltd. All rights reserved.
Item Details
| Item Type: | Contribution to Refereed Journal |
|---|---|
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Clinical sciences |
| Research Field: | Infectious diseases |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Clinical health not elsewhere classified |
| UTAS Author: | Cooley, MA (Associate Professor Margaret Cooley) |
| ID Code: | 53381 |
| Year Published: | 2008 |
| Web of Science® Times Cited: | 59 |
| Deposited By: | Menzies Institute for Medical Research |
| Deposited On: | 2008-12-04 |
| Last Modified: | 2008-12-04 |
| Downloads: | 0 |
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