eCite Digital Repository
Increased elongase and desaturase gene expression with stearidonic acid enriched diet does not enhance long-chain (n-3) content of seawater Atlantic salmon (Salmo salar L.)
Citation
Miller, MR and Bridle, AR and Nichols, PD and Carter, CG, Increased elongase and desaturase gene expression with stearidonic acid enriched diet does not enhance long-chain (n-3) content of seawater Atlantic salmon (Salmo salar L.), The Journal of Nutrition, 138, (11) pp. 2179-2185. ISSN 0022-3166 (2008) [Refereed Article]
![]() | PDF Restricted - Request a copy 555Kb |
Copyright Statement
Copyright © 2008 the Journal of Nutrition by the American Society for Nutrition
Official URL: http://jn.nutrition.org/
DOI: doi:10.3945/jn.108.091702
Abstract
Atlantic salmon (Salmo salar L.) can produce (n-3) long-chain (LC)-PUFA when fed biosynthetic precursors. This has
potential for developing sustainable aquafeeds. Echium oil (EO) is rich in stearidonic acid [SDA; 18:4(n-3)] and bypasses the
initial D6 desaturase (FAD6) step in the (n-3) LC-PUFA biosynthetic pathway. EO was fed to seawater Atlantic salmon for
12 wk and compared with fish fed a diet containing canola oil (CO), a source of a-linolenic acid [ALA; 18:3(n-3)] or fish oil
(FO) that provides (n-3) LC-PUFA. Fatty acid (FA) composition of liver, white muscle, and whole fish was measured to
show whether dietary precursors were endogenously biosynthesized to LC-PUFA. Gene expression of liver FA elongase
and FAD5 was upregulated in EO fish compared with FO fish. Furthermore, dietary precursors affected the FA
concentrations of direct biosynthetic products in all tissues. The increased gene expression in the EO fish was reflected by
an increased FA concentration of eicosapentaenoic acid [20:5(n-3)] in the liver compared with the CO fish. However, the
high concentrations of (n-3) LC-PUFA found in seawater Atlantic salmon fed diets rich in FO were not attained via
biosynthesis from precursors (ALA or SDA) in diets.
Item Details
Item Type: | Refereed Article |
---|---|
Research Division: | Agricultural, Veterinary and Food Sciences |
Research Group: | Fisheries sciences |
Research Field: | Aquaculture |
Objective Division: | Animal Production and Animal Primary Products |
Objective Group: | Fisheries - aquaculture |
Objective Field: | Fisheries - aquaculture not elsewhere classified |
UTAS Author: | Miller, MR (Dr Matthew Miller) |
UTAS Author: | Bridle, AR (Associate Professor Andrew Bridle) |
UTAS Author: | Carter, CG (Professor Chris Carter) |
ID Code: | 53322 |
Year Published: | 2008 |
Web of Science® Times Cited: | 44 |
Deposited By: | NC Marine Conservation and Resource Sustainability |
Deposited On: | 2008-11-25 |
Last Modified: | 2015-02-05 |
Downloads: | 0 |
Repository Staff Only: item control page