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Use of contactless conductivity detection for non-invasive characterisation of monolithic stationary-phase coatings for application in capillary ion chromatography

Citation

Gillespie, E and Connolly, D and Macka, M and Nesterenko, PN and Paull, B, Use of contactless conductivity detection for non-invasive characterisation of monolithic stationary-phase coatings for application in capillary ion chromatography, Analyst, 132, (12) pp. 1238-1245. ISSN 0003-2654 (2007) [Refereed Article]

DOI: doi:10.1039/b711350a

Abstract

A capacitively-coupled contactless conductivity detector (C4D) has been utilised as an on-capillary detector within a capillary ion chromatograph, incorporating a reversed-phase monolithic silica capillary column semi-permanently modified with a suitable ionic surfactant. The monolithic capillary column (150 × 0.1 mm i.d.) was modified using sodium dioctyl sulfosuccinate (DOSS), an anionic surfactant, for the separation of small inorganic and organic cations. With the use of the on-capillary conductivity detector, the longitudinal homogeneity and temporal stability of the coating were investigated. The approach allowed a detailed non-invasive observation of the nature of the ion-exchange coating over time, and an example of an application of the technique to produce a longitudinal stationary-phase charge gradient is shown. An investigation of the basis of the measured on-capillary conductivity was carried out with a counter ion study, clearly showing the on-capillary detection technique could also distinguish between chemical forms of the immobilised ion exchanger. The above method was used to produce a stable and homogeneously-modified monolithic ion-exchange capillary column, for application to the separation of inorganic alkaline earth cations and amino acids. © The Royal Society of Chemistry.

Item Details

Item Type:Refereed Article
Research Division:Physical Sciences
Research Group:Optical Physics
Research Field:Photonics, Optoelectronics and Optical Communications
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Nesterenko, PN (Professor Pavel Nesterenko)
Author:Paull, B (Professor Brett Paull)
ID Code:51213
Year Published:2007
Web of Science® Times Cited:30
Deposited By:Chemistry
Deposited On:2007-08-01
Last Modified:2011-08-18
Downloads:0

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