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Enlarged Virchow-Robin spaces in a psychotic woman


Pridmore, S and McInerney, G and Ahmadi, J and Rybak, M, Enlarged Virchow-Robin spaces in a psychotic woman, Journal of Psychiatric Intensive Care, 3, (1) pp. 49-54. ISSN 1742-6464 (2007) [Professional, Non Refereed Article]

DOI: doi:10.1017/S1742646407001069


Background and case description: Virchow-Robin spaces are fluid filled perivascular spaces in the brain which are rarely found in asymptomatic children. Their frequency increases with age and they are associated with cognitive decline in otherwise healthy elderly. They are common in high altitude mountain climbers, mild traumatic brain injury and in certain hereditary vascular diseases. In children they are associated with mental retardation, developmental delay and headache. They have been identified in children with autistic disorder. We describe a 28 year old female with severe catatonia, auditory hallucinations and delusions, and prominent Virchow-Robin spaces, who responded to ECT and olanzapine. Conclusion: MRI was valuable in the management of this case. While prominent Virchow-Robin spaces may have been a coincidental finding (not aetiologically significant) there was loss of brain parenchyma and we believe this contributed to the severity of the presentation and suggests a less favourable prognosis. © 2007, NAPICU. All rights reserved.

Item Details

Item Type:Professional, Non Refereed Article
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:Mental health services
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Mental health
UTAS Author:Pridmore, S (Professor Saxby Pridmore)
UTAS Author:Rybak, M (Dr Marzena Rybak)
ID Code:50412
Year Published:2007
Deposited By:Psychiatry
Deposited On:2007-08-01
Last Modified:2008-02-25

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