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Thermotolerance of L3 Ostertagia (Teladorsagia) circumcincta and some of its enzymes
journal contribution
posted on 2023-05-16, 21:03 authored by Walker, LR, Simcock, DC, Neale, JD, Simpson, HV, Brown, SCParasitic nematodes of ruminants can be expected to experience temperatures in excess of 40 °C in faeces on pasture and, perhaps, in the host. L3 Ostertagia (Teladorsagia) circumcincta survived for at least 90 min at 45 °C in vitro in water, but the larvae were inactivated rapidly by only slightly higher temperatures. The glycolytic enzymes hexokinase and pyruvate kinase were inactivated in a similar temperature range, whereas malate dehydrogenase maintained its activity at temperatures in excess of 50 °C. These data imply that the loss of glycolytic activity might explain the loss of larval motility at temperatures between 45 °C and 50 °C. © 2007 Elsevier B.V. All rights reserved.
History
Publication title
Veterinary ParasitologyVolume
146Issue
1-2Pagination
77-82ISSN
0304-4017Department/School
School of Health SciencesPublisher
Elsevier BVPlace of publication
NetherlandsRepository Status
- Restricted