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Thermotolerance of L3 Ostertagia (Teladorsagia) circumcincta and some of its enzymes


Walker, LR and Simcock, DC and Neale, JD and Simpson, HV and Brown, SC, Thermotolerance of L3 Ostertagia (Teladorsagia) circumcincta and some of its enzymes, Veterinary Parasitology, 146, (1-2) pp. 77-82. ISSN 0304-4017 (2007) [Refereed Article]

DOI: doi:10.1016/j.vetpar.2007.02.009


Parasitic nematodes of ruminants can be expected to experience temperatures in excess of 40 °C in faeces on pasture and, perhaps, in the host. L3 Ostertagia (Teladorsagia) circumcincta survived for at least 90 min at 45 °C in vitro in water, but the larvae were inactivated rapidly by only slightly higher temperatures. The glycolytic enzymes hexokinase and pyruvate kinase were inactivated in a similar temperature range, whereas malate dehydrogenase maintained its activity at temperatures in excess of 50 °C. These data imply that the loss of glycolytic activity might explain the loss of larval motility at temperatures between 45 °C and 50 °C. © 2007 Elsevier B.V. All rights reserved.

Item Details

Item Type:Refereed Article
Research Division:Biological Sciences
Research Group:Biochemistry and cell biology
Research Field:Enzymes
Objective Division:Animal Production and Animal Primary Products
Objective Group:Livestock raising
Objective Field:Sheep for wool
UTAS Author:Brown, SC (Dr Simon Brown)
ID Code:50064
Year Published:2007
Web of Science® Times Cited:5
Deposited By:Health Sciences A
Deposited On:2007-08-01
Last Modified:2011-11-30

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