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The respiratory effects of chloramine-T exposure in seawater acclimated and amoebic gill disease-affected Atlantic salmon Salmo salar L

Citation

Leef, MJ and Harris, J and Powell, MD, The respiratory effects of chloramine-T exposure in seawater acclimated and amoebic gill disease-affected Atlantic salmon Salmo salar L, Aquaculture, 266, (1-4) pp. 77-86. ISSN 0044-8486 (2007) [Refereed Article]

DOI: doi:10.1016/j.aquaculture.2006.12.032

Abstract

The aim of the present study was to examine the respiratory effects of chloramine-T, a proposed novel chemotherapeutic treatment for seawater-acclimated Atlantic salmon Salmo salar (L.) affected by amoebic gill disease (AGD). Following a surgical recovery period of 20-24 h, fish, both healthy (N = 21) and AGD-affected (N = 13) were exposed to either a 1-hour pulse of seawater containing chloramine-T at a therapeutic concentration of 10 mg L - 1 (experimental), or 100 ml of sterile seawater (sham-treated controls). Arterial blood samples were repeatedly taken from a dorsal aortic catheter prior to exposure (0 h), immediately following exposure (1 h) and then at 3, 6, 12 and 24 h and various respiratory parameters measured. Results showed that there were no significant effects relating to chloramine-T exposure regardless of disease status. Additional examination of the pH-bicarbonate diagrams confirmed that there was minimal acid-base disturbance in fish exposed to chloramine-T regardless of disease status. Significant changes seen within the examined haematological parameters of both healthy and AGD-affected fish appeared to be related to the repeated withdrawal of blood for analysis of respiratory parameters. Overall these results suggest that the use of chloramine-T in full-strength seawater at the therapeutic concentration of 10 mg L - 1 for 1 h had no significant respiratory effect in healthy or AGD-affected Atlantic salmon. Additionally, these results help to highlight the potential beneficial use of chloramine-T as a commercial treatment for gill diseased in marine Atlantic salmon. © 2007.

Item Details

Item Type:Refereed Article
Research Division:Agricultural and Veterinary Sciences
Research Group:Fisheries Sciences
Research Field:Aquaculture
Objective Division:Animal Production and Animal Primary Products
Objective Group:Fisheries - Aquaculture
Objective Field:Fisheries - Aquaculture not elsewhere classified
Author:Leef, MJ (Dr Melanie Leef)
Author:Harris, J (Dr James Harris)
Author:Powell, MD (Dr Mark Powell)
ID Code:49818
Year Published:2007
Web of Science® Times Cited:5
Deposited By:TAFI - Aquaculture
Deposited On:2007-08-01
Last Modified:2011-09-20
Downloads:0

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