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Rheumatic manifestations of lymphoproliferative disorders
Citation
Kiltz, U and Brandt, J and Zochling, JM and Braun, J, Rheumatic manifestations of lymphoproliferative disorders, Clinical and Experimental Rheumatology, 25, (1) pp. 35-39. ISSN 0392-856X (2007) [Refereed Article]
Abstract
Objective: The association between musculoskeletal features and lymphoproliferative disorders as well as the association of rheumatic diseases with an increased risk of malignancies is well-known. Methods: This paper describes three patients with inflammatory joint diseases treated with disease modifying antirheumatic drugs who developed lymphoproliferative disorders either of an abnormal type or with unusual clinical features. Results: The difficulty in differentiating the musculoskeletal symptoms of an underlying lymphoproliferative disease from the features of the rheumatic disease itself with special regard to treatment with disease-modifying antirheumatic drugs including biologics is emphasised on the example of patient 1. Patient 2 presented with a rare type of lymphoma and had been mistakenly diagnosed as having seronegative RA. The last patient with oligoarthritis represents an example of the sarcoidosis-lymphoma syndrome. Conclusion: This article addresses several of the problems rheumatologists may experience with the various rheumatologic manifestations of lymphoproliferative disorders. Until more definitive data are available, patients who develop unexpected arthritis should be considered for histologic biopsy to rule out coexistent neoplasia.
Item Details
Item Type: | Refereed Article |
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Research Division: | Health Sciences |
Research Group: | Epidemiology |
Research Field: | Epidemiology not elsewhere classified |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Zochling, JM (Dr Jane Zochling) |
ID Code: | 49160 |
Year Published: | 2007 |
Web of Science® Times Cited: | 5 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2007-08-01 |
Last Modified: | 2010-05-19 |
Downloads: | 0 |
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