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The use of a 'liquid' electrode in hepatic electrolysis
Citation
Finch, JG and Fosh, BG and Anthony, AA and Texler, M and Pearson, S and Dennison, AR and Maddern, GJ, The use of a 'liquid' electrode in hepatic electrolysis, Journal of Surgical Research, 120, (2) pp. 272-277. ISSN 0022-4804 (2004) [Refereed Article]
DOI: doi:10.1016/j.jss.2004.03.019
Abstract
Background The use of direct current electrolysis as a local nonthermal ablative technique for colorectal liver metastases promises to be a simple, safe, and effective therapy. Under general anesthesia, electrolysis is presently limited to tumors smaller than 5 cm, due to the protracted nature of its administration. In an attempt to enhance the effect of electrolysis, a direct current was passed through a preinjected bolus of acetic acid. Methods The effect of a combination of electrolysis and an injection of acetic acid was tested in the liver of eight normal pigs. The volumes of necrosis caused were analyzed. Results Acetic acid independently produced a volume of necrosis but did not provide a volumetric or rate advantage when used in combination with a direct current. Statistically, the only main effect on the volume of necrosis was a result of electrolysis. Conclusion The use of 50% acetic acid to augment the efficacy of direct current electrolysis cannot be recommended. © 2004 Elsevier Inc. All rights reserved.
Item Details
Item Type: | Refereed Article |
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Research Division: | Biomedical and Clinical Sciences |
Research Group: | Oncology and carcinogenesis |
Research Field: | Oncology and carcinogenesis not elsewhere classified |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Treatment of human diseases and conditions |
UTAS Author: | Pearson, S (Dr Sue Pearson) |
ID Code: | 48884 |
Year Published: | 2004 |
Web of Science® Times Cited: | 3 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2007-08-01 |
Last Modified: | 2011-11-17 |
Downloads: | 0 |
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