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Mice that are congenic for the char2 locus are susceptible to malaria


Burt, RA and Marshall, VM and Wagglen, J and Rodda, FR and Senyschen, D and Baldwin, TM and Buckingham, LA and Foote, SJ, Mice that are congenic for the char2 locus are susceptible to malaria, Infection and Immunity, 70, (8) pp. 4750-4753. ISSN 0019-9567 (2002) [Refereed Article]

DOI: doi:10.1128/IAI.70.8.4750-4753.2002


A major advance has been made towards the positional cloning of char2 (a quantitative trait locus encoding resistance to Plasmodium chabaudi malaria). Mice congenic for the locus have been used to fine map the gene and to prove that char2 plays a significant role in the outcome of malarial infection, independently of other resistance loci.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Medical genetics (excl. cancer genetics)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Foote, SJ (Professor Simon Foote)
ID Code:48748
Year Published:2002
Web of Science® Times Cited:19
Deposited By:Menzies Institute for Medical Research
Deposited On:2007-08-01
Last Modified:2012-03-14

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