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Sorbents with immobilized glycopeptide antibiotics for separating optical isomers by high-performance liquid chromatography
Citation
Kuznetsov, MA and Nesterenko, PN and Vasiarov, GG and Staroverov, SM, Sorbents with immobilized glycopeptide antibiotics for separating optical isomers by high-performance liquid chromatography, Applied Biochemistry and Microbiology, 42, (6) pp. 536-544. ISSN 0003-6838 (2006) [Refereed Article]
DOI: doi:10.1134/S0003683806060020
Abstract
Chiral sorbents for HPLC separation of optical isomers carrying glycopeptide antibiotics (eremomycin or its eremosaminyl aglycon, ristomycin, or vancomycin) fixed onto the surface of silica gel have been synthesized. The patterns of the retention and separation of profen isomers and their dependence on the nature of the chiral selector and the eluant composition have been studied. The sorbents were shown to be highly enantiospecific in separating the isomers of α-amino-, α-hydroxy-, and α-methylphenylcarboxylic acids (profens). © 2006 Nauka/Interperiodica.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Research Division: | Chemical Sciences |
| Research Group: | Analytical Chemistry |
| Research Field: | Separation Science |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Chemical Sciences |
| Author: | Nesterenko, PN (Professor Pavel Nesterenko) |
| ID Code: | 47771 |
| Year Published: | 2006 |
| Web of Science® Times Cited: | 9 |
| Deposited By: | Chemistry |
| Deposited On: | 2007-09-21 |
| Last Modified: | 2009-11-13 |
| Downloads: | 0 |
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