eCite Digital Repository

Sorbents with immobilized glycopeptide antibiotics for separating optical isomers by high-performance liquid chromatography

Citation

Kuznetsov, MA and Nesterenko, PN and Vasiarov, GG and Staroverov, SM, Sorbents with immobilized glycopeptide antibiotics for separating optical isomers by high-performance liquid chromatography, Applied Biochemistry and Microbiology, 42, (6) pp. 536-544. ISSN 0003-6838 (2006) [Refereed Article]

DOI: doi:10.1134/S0003683806060020

Abstract

Chiral sorbents for HPLC separation of optical isomers carrying glycopeptide antibiotics (eremomycin or its eremosaminyl aglycon, ristomycin, or vancomycin) fixed onto the surface of silica gel have been synthesized. The patterns of the retention and separation of profen isomers and their dependence on the nature of the chiral selector and the eluant composition have been studied. The sorbents were shown to be highly enantiospecific in separating the isomers of α-amino-, α-hydroxy-, and α-methylphenylcarboxylic acids (profens). © 2006 Nauka/Interperiodica.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Nesterenko, PN (Professor Pavel Nesterenko)
ID Code:47771
Year Published:2006
Web of Science® Times Cited:9
Deposited By:Chemistry
Deposited On:2007-09-21
Last Modified:2009-11-13
Downloads:0

Repository Staff Only: item control page