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Fabrication of porous polymer monoliths covalently attached to the walls of channels in plastic microdevices


Stachowiak, TB and Rohr, T and Hilder, EF and Peterson, DS and Yi, M and Svec, F and Frechet, JMJ, Fabrication of porous polymer monoliths covalently attached to the walls of channels in plastic microdevices, Electrophoresis, 24, (21) pp. 3689-3693. ISSN 0173-0835 (2003) [Refereed Article]

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DOI: doi:10.1002/elps.200305536


UV-initiated grafting of plastic tubes and microfluidic chips with ethylene diacrylate followed by the preparation of porous polymer monoliths has been studied. The first step affords a thin grafted layer of polymer with a multiplicity of pendent double bonds that are then used in the second step for covalent attachment of the monolith to the wall. As clearly seen on scanning electron micrographs, this procedure prevents the formation of voids at the monolith-channel interface a problem that has always plagued approaches involving bulk polymerization in nontreated channels due to the shrinkage of the monolith during the polymerization process and its lack of compatibility with the material of the device. Irradiation with UV light through a photomask allows precise patterning specifying both the area subjected to surface modification and the location of the monolith within specific areas of the device.

Item Details

Item Type:Refereed Article
Keywords:Microchip / Microfluidic / Miniaturization / Monolith / Porous polymer
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Hilder, EF (Professor Emily Hilder)
UTAS Author:Svec, F (Dr Frantisek Svec)
ID Code:47714
Year Published:2003
Web of Science® Times Cited:123
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2007-08-01
Last Modified:2010-03-23
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