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Selenium status in Southern Tasmania


Jacobson, GA and Tong, YC and Townsend, AT and Featherstone, AM and Ball, MJ and Robertson, IK and Peterson, GM, Selenium status in Southern Tasmania, European Journal of Clinical Nutrition, 61, (9) pp. 1057-1063. ISSN 0954-3007 (2007) [Refereed Article]

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Copyright 2011 Nature Publishing Group

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DOI: doi:10.1038/sj.ejcn.1602628


Objective: To assess the selenium status of Southern Tasmanians. Design: Cross-sectional. Settings: One thousand and five hundred adults randomly selected from the electoral roll living in the Greater Hobart region of Southern Tasmania, Australia, were invited to participate. Subjects: The overall response rate was 22% (335-1500). Interventions: A venous blood sample was collected and a questionnaire administered (consisting of brief demographic details and health questions) to subjects who granted informed consent. A previously validated assay using magnetic sector ICP-MS was employed for plasma analysis. Results: Total plasma selenium levels for this sample population were normally distributed with a mean level of 110 μg/l (range 67 μg/l) indicating that the majority of the subjects were not selenium-depleted (71% with levels greater than 100 μg/l). Adjustment for differential age/gender response rates produced similar values. More women under 50 (42%) and men over 50 (32%) had selenium levels <100 μg/l with the potential for sub-optimal selenoprotein activity. Low education attainment was associated with low total selenium level (P < 0.02). Conclusions: The majority of participants were not deficient in selenium. Given the narrow therapeutic window of supplementation, dietary advice to increase foods rich in selenium, particularly to higher risk groups, may be an effective means of increasing plasma selenium toward target levels.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Pharmaceutical sciences
Objective Division:Health
Objective Group:Other health
Objective Field:Other health not elsewhere classified
UTAS Author:Jacobson, GA (Associate Professor Glenn Jacobson)
UTAS Author:Tong, YC (Miss Emily Tong)
UTAS Author:Townsend, AT (Associate Professor Ashley Townsend)
UTAS Author:Featherstone, AM (Dr Alison Featherstone)
UTAS Author:Ball, MJ (Professor Madeleine Ball)
UTAS Author:Robertson, IK (Dr Iain Robertson)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
ID Code:44575
Year Published:2007
Web of Science® Times Cited:7
Deposited By:Pharmacy
Deposited On:2007-08-01
Last Modified:2011-10-04

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