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The regioselective synthesis of aryl pyrroles
Citation
Smith, JA and Ng, M and White, J, The regioselective synthesis of aryl pyrroles, Organic and Biomolecular Chemistry, 4, (12) pp. 2477-2482. ISSN 1477-0520 (2006) [Refereed Article]
DOI: doi:10.1039/b604692d
Abstract
Pyrrole is a unique aromatic molecule as it can readily undergo substitution at all five positions but obtaining the desired regioisomer can prove difficult to control. We now report our results on the regioselective arylation of pyrrole, utilizing selective halogenation and the Suzuki-Miyaura reaction to prepare C4-, C5- and C3-aryl derivatives. We have applied this methodology to the synthesis of lamellarin O dimethyl ether, an intermediate in the synthesis of lukinol A. © The Royal Society of Chemistry 2006.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Research Division: | Chemical Sciences |
| Research Group: | Organic Chemistry |
| Research Field: | Organic Chemical Synthesis |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Chemical Sciences |
| Author: | Smith, JA (Associate Professor Jason Smith) |
| Author: | Ng, M (Miss Sarah Ng) |
| ID Code: | 43149 |
| Year Published: | 2006 |
| Web of Science® Times Cited: | 31 |
| Deposited By: | Chemistry |
| Deposited On: | 2006-08-01 |
| Last Modified: | 2007-04-03 |
| Downloads: | 0 |
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