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A General and Efficient Approach to the Proposed Structures of Frog Toxins: The 5-Alkylindolizidines
journal contribution
posted on 2023-05-16, 18:49 authored by Gourlay, BS, Little, I, Ryan, JH, Jason SmithJason SmithThe structural assignments of a number of bicyclic alkaloids isolated from frogs have been reassigned or questioned after synthesis of the proposed structures. Herein we report a practical and short formal synthesis of the 5-alkylindolizidine core, from readily available α-amino acids or homoserine that could be utilized to support structural assignments.
History
Publication title
Natural Product CommunicationsIssue
10Pagination
831-837ISSN
1934-578XDepartment/School
School of Natural SciencesPublisher
Natural Product Inc.Place of publication
Westerville USARepository Status
- Restricted