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A General and Efficient Approach to the Proposed Structures of Frog Toxins: The 5-Alkylindolizidines

Citation

Gourlay, BS and Little, I and Ryan, JH and Smith, JA, A General and Efficient Approach to the Proposed Structures of Frog Toxins: The 5-Alkylindolizidines, Natural Product Communications, 1, (10) pp. 831-837. ISSN 1934-578X (2006) [Refereed Article]

Abstract

The structural assignments of a number of bicyclic alkaloids isolated from frogs have been reassigned or questioned after synthesis of the proposed structures. Herein we report a practical and short formal synthesis of the 5-alkylindolizidine core, from readily available α-amino acids or homoserine that could be utilized to support structural assignments.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Organic Chemistry
Research Field:Organic Chemical Synthesis
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Gourlay, BS (Dr Brendon Gourlay)
Author:Little, I (Mr Ian Little)
Author:Smith, JA (Associate Professor Jason Smith)
ID Code:43125
Year Published:2006
Web of Science® Times Cited:2
Deposited By:Chemistry
Deposited On:2006-08-01
Last Modified:2007-05-17
Downloads:0

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