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A General and Efficient Approach to the Proposed Structures of Frog Toxins: The 5-Alkylindolizidines

journal contribution
posted on 2023-05-16, 18:49 authored by Gourlay, BS, Little, I, Ryan, JH, Jason SmithJason Smith
The structural assignments of a number of bicyclic alkaloids isolated from frogs have been reassigned or questioned after synthesis of the proposed structures. Herein we report a practical and short formal synthesis of the 5-alkylindolizidine core, from readily available α-amino acids or homoserine that could be utilized to support structural assignments.

History

Publication title

Natural Product Communications

Issue

10

Pagination

831-837

ISSN

1934-578X

Department/School

School of Natural Sciences

Publisher

Natural Product Inc.

Place of publication

Westerville USA

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences

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