University of Tasmania
Browse
368.pdf (117.99 kB)

Comparison of Different Contactless Conductivity Detectors for the Determination of Small Inorganic Ions by Capillary Electrophoresis

Download (117.99 kB)
journal contribution
posted on 2023-05-16, 18:46 authored by Kuban, P, Evenhuis, CJ, Miroslav MackaMiroslav Macka, Paul HaddadPaul Haddad, Hauser, PC
The analytical performance parameters of four different contactless conductivity detectors for capillary electrophoresis were determined. These detectors were designed either with a miniature cell for versatility, with high voltage excitation for high sensitivity or with a battery power supply for field application. One of the units is commercially available. The plate numbers and reproducibility of peak areas (typically about 2%) were very similar, indicating that these parameters are generally limited by the separation and injection procedures rather than the detectors. The linear dynamic ranges are better than 2 orders of magnitude for all detectors and the correlation coefficients were also almost identical. Significant differences were found with regard to the detection limits. For the detector with a miniature cell, which lacks an in-cell amplifier, the detection limit was typically 1.5 μM for the inorganic ions tested (K+, Ca2+, Na+, Mg2+, Li +, Cl-, NO3 - and SO4 2-), while with the other 3 detectors this parameter was as low as about 0.1 μM. The use of buffer solutions with relatively high background conductivity was found to lead to detection limits which were up to one order of magnitude higher. The extent of deterioration of this parameter with buffer conductivity was found to be related to the excitation voltage and was most pronounced for the high voltage detector. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

History

Publication title

Electroanalysis

Volume

18

Issue

13-14

Pagination

1289-1296

ISSN

1040-0397

Department/School

School of Natural Sciences

Publisher

Wiley

Place of publication

Weinheim

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences

Usage metrics

    University Of Tasmania

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC