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Evaluating the use of a portable ultrasound machine to quantify intima-media thickness and flow-mediated dilatation: Agreement between measurements from two ultrasound machines

Citation

Magnussen, CG and Fryer, JL and Venn, A and Laakkonen, M and Raitakan, O, Evaluating the use of a portable ultrasound machine to quantify intima-media thickness and flow-mediated dilatation: Agreement between measurements from two ultrasound machines, Ultrasound in Medicine and Biology, 32, (9) pp. 1323-1329. ISSN 0301-5629 (2006) [Refereed Article]

DOI: doi:10.1016/j.ultrasmedbio.2006.05.009

Abstract

Flow-mediated dilation (FMD) and common carotid intima-media thickness (CIMT) are intermediate endpoints for cardiovascular disease. The purpose of this study was to determine whether a portable ultrasound machine was capable of valid measurements of FMD and CIMT compared with a clinic-based machine under similar conditions. Vascular images were taken on 23 apparently healthy young adults with the portable type and clinic type instruments. The analyses revealed a high level of agreement between the two machines for measurements of maximum CIMT (mean difference [MD] = -0.025 mm, limits of agreement [LOA] = -0.080, 0.029 mm), mean CIMT (MD = 0.001 mm, LOA = -0.065, 0.065 mm) and FMD measures of brachial diameter (baseline MD = 0.199 mm, LOA = -0.210, 0.608 mm, maximum MD = 0.218 mm, LOA = -0.162, 0.597 mm). Reasonable agreement was found for %FMD measurements (MD = 0.27%, LOA = -4.91, 5.44%). The within-machine coefficient of variation results for maximum CIMT (5.0%), mean CIMT (4.3%), baseline (6.3%) and maximum (5.4%) brachial diameter and %FMD (30.1%) were comparable with normal within-subject variation. We conclude that the portable ultrasound machine can provide measurements of FMD and CIMT that are highly comparable with measurements obtained from a clinic-based machine under similar clinical conditions. (E-mail: cmagnuss@utas.edu.au). © 2006 World Federation for Ultrasound in Medicine & Biology.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Health and Support Services
Objective Field:Diagnostic Methods
Author:Magnussen, CG (Dr Costan Magnussen)
Author:Fryer, JL (Ms Jayne Fryer)
Author:Venn, A (Professor Alison Venn)
ID Code:42889
Year Published:2006
Web of Science® Times Cited:18
Deposited By:Menzies Institute for Medical Research
Deposited On:2006-08-01
Last Modified:2007-04-04
Downloads:0

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