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The Mechanisms of Neuropathic Pain; an Overview for Psychiatrists

Citation

Pridmore, S and Pasha, I and Kahn, U, The Mechanisms of Neuropathic Pain; an Overview for Psychiatrists, German Journal of Psychiatry, 5, (1) pp. 35-39. ISSN 1433-1055 (2002) [Refereed Article]

Abstract

Objective: To present an overview of the mechanisms of neuropathic pain. Method: An extensive review of the scientific literature. Results: Neuroplastic changes are described under the headings of: ectopic discharge, sensitization of sensory terminals, cross-excitation, neurotransmitter change, coupling between the sympathetic and sensory nervous systems, spinal cord reorganization, spinal cord increased excitability, spinal cord decreased inhibition, supraspinal influences. Conclusions: These mechanisms increase our understanding of the patient with neuropathic pain and open the door for therapeutic advances in this field. They also extend our understanding of the nature of the nervous system more generally, and may provide pathophysiologic models of psychiatric disorders.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Psychiatry (incl. Psychotherapy)
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Mental Health
Author:Pridmore, S (Professor Saxby Pridmore)
ID Code:41466
Year Published:2002
Deposited By:Psychiatry
Deposited On:2007-01-15
Last Modified:2007-01-15
Downloads:0

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