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Characterization of a clinical Vibrio cholerae O139 isolate from Mexico


Parveen, S and Farrah, SR and Gonzalez-Bonilla, c and Zamudio, AV and Tamplin, ML, Characterization of a clinical Vibrio cholerae O139 isolate from Mexico, Canadian Journal of Microbiology, 49, (1) pp. 65-70. ISSN 0008-4166 (2003) [Refereed Article]

DOI: doi:10.1139/w03-004


Pathogenic strains of Vibrio cholerae O139 possess the cholera toxin A subunit (ctxA) gene as well as the gene for toxin co-regulated pili (tcpA). We report the isolation of a ctxA-negative, tcpA-negative V. cholerae O139 strain (INDRE1) from a patient in Mexico diagnosed with gastrointestinal illness. Certain phenotypic characteristics of this strain were identical to those of V. cholerae O1 biotype El Tor. Unlike ctxA-positive V. cholerae O139 strains, this strain was sensitive to a wide panel of antibiotics, including ampicillin, chloramphenicol, ciprofloxacin, gentamicin, furazolidone, nalidixic acid, nitrofurantoin, tetracycline, trimethoprim-sulfamethoxazole, and streptomycin, but was resistant to polymyxin B. Ribotype and pulsed-field gel electrophoresis profiles of INDRE1 differed from those of ctxA-positive V. choterae O139 and other V. cholerae strains. Phenotypic characteristics of the Mexico strain were similar to those reported for V. cholerae O139 isolates from Argentina and Sri Lanka.

Item Details

Item Type:Refereed Article
Research Division:Biological Sciences
Research Group:Microbiology
Research Field:Bacteriology
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Food safety
UTAS Author:Tamplin, ML (Professor Mark Tamplin)
ID Code:40925
Year Published:2003
Web of Science® Times Cited:3
Deposited By:Agricultural Science
Deposited On:2006-08-01
Last Modified:2006-11-20

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