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Quantitation of suspected allergens in fragrances (Part 1): evaluation of comprehensive two-dimensional gas chromatography for quality control
Citation
Shellie, RA and Marriott, PJ and Chaintreau, A, Quantitation of suspected allergens in fragrances (Part 1): evaluation of comprehensive two-dimensional gas chromatography for quality control, Flavour and Fragrance Journal, 19, (2) pp. 91-98. ISSN 0882-5734 (2004) [Refereed Article]
DOI: doi:10.1002/ffj.1334
Abstract
An evaluation of comprehensive two-dimensional (2D) gas chromatography (GC×GC) was performed to assess its suitability for the analysis of volatile fragrance components, recognized by the European Commission's Scientific Committee on Cosmetics and other Non-food Products (SCCNFP) as possible skin sensitizers. The 24 volatile components listed by the SCCNFP were baseline-resolved or better within one 30 min analysis. High-quality calibration data for standard mixtures were obtained, with R2 > 0.998 over the concentration range 2-1000 mg/l. However, the analysis of small spiked amounts of target compounds in truly complex fragrances was problematic, due to uncertainty in component assignment. The benefits and limitations of GC×GC are reported, and a discussion of the proposed directions for the solution of this analysis is provided. Copyright © 2004 John Wiley & Sons, Ltd. Copyright © 2004 John Wiley & Sons, Ltd.
Item Details
Item Type: | Refereed Article |
---|---|
Research Division: | Chemical Sciences |
Research Group: | Analytical chemistry |
Research Field: | Separation science |
Objective Division: | Manufacturing |
Objective Group: | Instrumentation |
Objective Field: | Scientific instruments |
UTAS Author: | Shellie, RA (Associate Professor Robert Shellie) |
ID Code: | 36272 |
Year Published: | 2004 |
Web of Science® Times Cited: | 53 |
Deposited By: | Chemistry |
Deposited On: | 2007-11-02 |
Last Modified: | 2007-11-02 |
Downloads: | 0 |
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