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Quantitation of suspected allergens in fragrances (Part 1): evaluation of comprehensive two-dimensional gas chromatography for quality control

Citation

Shellie, RA and Marriott, PJ and Chaintreau, A, Quantitation of suspected allergens in fragrances (Part 1): evaluation of comprehensive two-dimensional gas chromatography for quality control, Flavour and Fragrance Journal, 19, (2) pp. 91-98. ISSN 0882-5734 (2004) [Refereed Article]

DOI: doi:10.1002/ffj.1334

Abstract

An evaluation of comprehensive two-dimensional (2D) gas chromatography (GC×GC) was performed to assess its suitability for the analysis of volatile fragrance components, recognized by the European Commission's Scientific Committee on Cosmetics and other Non-food Products (SCCNFP) as possible skin sensitizers. The 24 volatile components listed by the SCCNFP were baseline-resolved or better within one 30 min analysis. High-quality calibration data for standard mixtures were obtained, with R2 > 0.998 over the concentration range 2-1000 mg/l. However, the analysis of small spiked amounts of target compounds in truly complex fragrances was problematic, due to uncertainty in component assignment. The benefits and limitations of GC×GC are reported, and a discussion of the proposed directions for the solution of this analysis is provided. Copyright © 2004 John Wiley & Sons, Ltd. Copyright © 2004 John Wiley & Sons, Ltd.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Manufacturing
Objective Group:Instrumentation
Objective Field:Scientific Instruments
Author:Shellie, RA (Associate Professor Robert Shellie)
ID Code:36272
Year Published:2004
Web of Science® Times Cited:45
Deposited By:Chemistry
Deposited On:2007-11-02
Last Modified:2007-11-02
Downloads:0

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