eCite Digital Repository
Comprehensive Two-Dimensional Gas Chromatography with Fast Enantioseparation
Citation
Shellie, RA and Marriott, P, Comprehensive Two-Dimensional Gas Chromatography with Fast Enantioseparation, Analytical Chemistry, 74, (20) pp. 5426-5430. ISSN 0003-2700 (2002) [Refereed Article]
Abstract
The development of fast chiral analysis for use in comprehensive two-dimensional gas chromatography in which a short second dimension enantioselective capillary column provides a route to precise measurement of chiral ratios of enantiomers is described. Retention times as short as 8 s are reported for (±)-limonene, with adequate enantioseparation maintained (Rs ∼ 1.0) on a 1-m cyclodextrin derivative-coated capillary column. Sufficiently fast elution on the second column was achieved by using GC/MS in which the subambient pressure (vacuum outlet) conditions promote increased diffusion coefficients and higher component volatility; a 4-fold reduction of second-dimension retention time was observed, as compared with ambient pressure outlet conditions. The enantiomeric distribution of several monoterpene compounds in bergamot essential oil is reported as a demonstration of the method. Total analysis time of the target components was ∼8.5 min.
Item Details
Item Type: | Refereed Article |
---|---|
Research Division: | Chemical Sciences |
Research Group: | Analytical chemistry |
Research Field: | Separation science |
Objective Division: | Manufacturing |
Objective Group: | Instrumentation |
Objective Field: | Scientific instruments |
UTAS Author: | Shellie, RA (Associate Professor Robert Shellie) |
ID Code: | 36263 |
Year Published: | 2002 |
Web of Science® Times Cited: | 91 |
Deposited By: | Chemistry |
Deposited On: | 2007-11-02 |
Last Modified: | 2007-11-02 |
Downloads: | 0 |
Repository Staff Only: item control page