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Annulation of pyrrole: application to the synthesis of indolizidine alkaloids
Citation
Amos, RIJ and Gourlay, BS and Molesworth, PP and Smith, JA and Sprod, OR, Annulation of pyrrole: application to the synthesis of indolizidine alkaloids, Tetrahedron, 61, (34) pp. 8226-8230. ISSN 0040-4020 (2005) [Refereed Article]
DOI: doi:10.1016/j.tet.2005.06.026
Abstract
The nucleophilicity of pyrrole has been exploited to rapidly assemble the bicyclic skeleton of the indolizidine alkaloids. The key sequence is the annulation of a second ring onto pyrrole from a γ-lactone and has been exploited in the synthesis of the natural products (±)-monomorine and (±)-indolizidine 209D. © 2005 Elsevier Ltd. All rights reserved.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Research Division: | Chemical Sciences |
| Research Group: | Organic chemistry |
| Research Field: | Organic chemical synthesis |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding knowledge |
| Objective Field: | Expanding knowledge in the chemical sciences |
| UTAS Author: | Amos, RIJ (Dr Ruth Amos) |
| UTAS Author: | Gourlay, BS (Dr Brendon Gourlay) |
| UTAS Author: | Molesworth, PP (Dr Peter Molesworth) |
| UTAS Author: | Smith, JA (Associate Professor Jason Smith) |
| UTAS Author: | Sprod, OR (Mr Owen Sprod) |
| ID Code: | 36236 |
| Year Published: | 2005 |
| Web of Science® Times Cited: | 57 |
| Deposited By: | Chemistry |
| Deposited On: | 2005-08-01 |
| Last Modified: | 2008-09-17 |
| Downloads: | 0 |
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