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Can nature's defence against malaria be mimicked by the development of host-directed therapies

Citation

Foote, SJ, Can nature's defence against malaria be mimicked by the development of host-directed therapies, Pharmacogenomics, 4, (3) pp. 141-142. ISSN 1470-269X (2004) [Refereed Article]


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Copyright Statement

2004 Nature Publishing Group

DOI: doi:10.1038/sj.tpj.6500241

Abstract

There is an evolutionary battle being fought and the battleground is the humble erythrocyte. The two foes are the genomes of the malarial parasites and their human host and the battle has been waging since the beginning of vertebrate evolution. On the one hand, the erythrocyte must ensure the oxygenation of tissues through its transport of oxygen and yet, on the other, it supplies the malarial parasite with an essential home during the prolonged blood-stage of the life cycle of this most ferocious of human pathogens.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Immunology
Research Field:Immunology not elsewhere classified
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Infectious Diseases
Author:Foote, SJ (Professor Simon Foote)
ID Code:34906
Year Published:2004
Web of Science® Times Cited:5
Deposited By:Menzies Centre
Deposited On:2005-07-29
Last Modified:2010-07-08
Downloads:0

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