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Mirror, mirror on the wall: viewing a mirror reflection of unilateral hand movements facilitates ipsilateral M1 excitability

Citation

Garry, MI and Loftus, AM and Summers, JJ, Mirror, mirror on the wall: viewing a mirror reflection of unilateral hand movements facilitates ipsilateral M1 excitability, Experimental Brain Research, 163, (1) pp. 118-122. ISSN 0014-4819 (2005) [Refereed Article]

DOI: doi:10.1007/s00221-005-2226-9

Abstract

Primary motor cortex (M1) excitability is modulated by both ipsilateral limb movement and passive observation of movement of the contralateral limb. An interaction of these effects within M1 may account for recent research suggesting improved functional recovery of the impaired arm following stroke by viewing a mirror reflection of movements of the unimpaired arm superimposed over the (unseen) impaired arm. This hypothesis was tested in the present study using single-pulse transcranial magnetic stimulation (TMS) in eight neurologically healthy subjects. Excitability of M1 ipsilateral to a phasic, unilateral hand movement was measured while subjects performed paced (1 Hz), unilateral index finger-thumb opposition movements. Motor evoked potentials (MEPs) were obtained from the inactive first dorsal interosseous (FDI) in each of four viewing conditions: Active (viewing the active hand), Central (viewing a mark positioned between hands), Inactive (viewing the inactive hand) and Mirror (viewing a mirror-reflection of the active hand in a mirror oriented in the mid-sagittal plane) and with both hands at rest (Rest). MEPs were significantly enhanced during ipsilateral hand movement compared with the Rest condition (P < 0.05). Largest MEPs were obtained in the Mirror condition, and this was significant compared with both the Inactive and Central viewing conditions (P < 0.05). There was no difference between the dominant and non-dominant hand. Excitability of M1 ipsilateral to a unilateral hand movement is facilitated by viewing a mirror reflection of the moving hand. This finding provides neurophysiological evidence supporting the application of mirror therapy in stroke rehabilitation. © Springer-Verlag 2005.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Human Movement and Sports Science
Research Field:Motor Control
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in Psychology and Cognitive Sciences
Author:Garry, MI (Dr Michael Garry)
Author:Loftus, AM (Mrs Andrea Loftus)
Author:Summers, JJ (Professor Jeffery Summers)
ID Code:33857
Year Published:2005
Funding Support:Australian Research Council (DP0345312)
Web of Science® Times Cited:125
Deposited By:Psychology
Deposited On:2005-08-01
Last Modified:2006-04-08
Downloads:0

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