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New approaches for fabrication of microfluidic capillary electrophoresis devices with on-chip conductivity detection
Citation
Guijt, RM and Baltussen, E and van der Steen, G and Schasfoort, RBM and Schlautmann, S and Billiet, HAH and Frank, J and van Dedem, GWK and van den Berg, A, New approaches for fabrication of microfluidic capillary electrophoresis devices with on-chip conductivity detection, Electrophoresis, 22, (2) pp. 235-241. ISSN 0173-0835 (2001) [Refereed Article]
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Copyright Statement
The definitive published version is available online at: http://interscience.wiley.com
DOI: doi:10.1002/1522-2683(200101)22:2<235::AID-ELPS235>3.0.CO;2-O
Abstract
In practice, microfluidic systems are based on the principles of capillary electrophoresis (CE), for a large part due to the simplicity of electroosmotic pumping. In this contribution, a universal conductivity detector is presented that allows detection of charged species down to the M level. Additionally, powderblasting is presented as a novel technique for direct etching of microfluidic networks. This method allows creation of features down to 50 m with a total processing time (design to device) of less than one day. The performance of powderblasted devices with integrated conductivity detection is illustrated by the separation of lithium, sodium, and potassium ions and that of fumaric, malic, and citric acid.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | Micro-total analysis systems • Micromachining • Capillary electrophoresis • Conductivity detection |
| Research Division: | Chemical Sciences |
| Research Group: | Analytical Chemistry |
| Research Field: | Instrumental Methods (excl. Immunological and Bioassay Methods) |
| Objective Division: | Manufacturing |
| Objective Group: | Instrumentation |
| Objective Field: | Scientific Instruments |
| Author: | Guijt, RM (Dr Rosanne Guijt) |
| ID Code: | 32952 |
| Year Published: | 2001 |
| Web of Science® Times Cited: | 96 |
| Deposited By: | Chemistry |
| Deposited On: | 2007-11-02 |
| Last Modified: | 2011-08-12 |
| Downloads: | 1 View Download Statistics |
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