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Patterns of peripheral steroid metabolism vary with sex, season, and tissue type in blotched blue-tongued lizards (Tiliqua nigrolutea)

Citation

Edwards, A and Jones, SM and Davies, NW, Patterns of peripheral steroid metabolism vary with sex, season, and tissue type in blotched blue-tongued lizards (Tiliqua nigrolutea), General and Comparative Endocrinology, 140, (1) pp. 14-24. ISSN 0016-6480 (2005) [Refereed Article]

DOI: doi:10.1016/j.ygcen.2004.10.001

Abstract

We examined sexual and seasonal variation in the ability of reproductively relevant tissues (liver, skin, adrenal gland, cloaca, kidney, renal sexual segment, epididymis, oviduct, muscle, testis, and ovary) to metabolise a primary steroid [testosterone (T) or estradiol (E2)] in the scincid lizard, Tiliqua nigrolutea. We observed considerable variation between sexes and across seasons in the patterns of conjugation and derivatisation of the primary steroids by these tissues. All tissues demonstrated the ability to conjugate the relevant primary steroid. Other general trends included increased conjugation by all tissues of gestating females, reduced metabolism of E2 by female tissues during late vitellogenesis, and reduced metabolism of T by males during early spermatogenesis. 5α-Dihydrotestosterone was the most commonly detected derivative in males, and production varied with season and tissue type. We suggest that seasonal variation in the ability of reproductively relevant tissues may be important in the physiological regulation of reproduction in this species. © 2004 Elsevier Inc. All rights reserved.

Item Details

Item Type:Refereed Article
Research Division:Biological Sciences
Research Group:Physiology
Research Field:Comparative Physiology
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Environmental Sciences
Author:Edwards, A (Dr Ashley Edwards)
Author:Jones, SM (Professor Susan Jones)
Author:Davies, NW (Associate Professor Noel Davies)
ID Code:32740
Year Published:2005
Web of Science® Times Cited:7
Deposited By:Zoology
Deposited On:2005-08-01
Last Modified:2008-05-14
Downloads:0

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