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An Algebraic Model of RNA Duplex Formation


Bashford, JD and Jarvis, PD, An Algebraic Model of RNA Duplex Formation, Biopolymers, 73, (6) pp. 657-667. ISSN 0006-3525 (2004) [Refereed Article]

DOI: doi:10.1002/bip.20022


We propose a simple algebraic description of the two-body interactions of bases in RNA thermodynamics showing in detail qualitative equivalence with conventional nearest-neighbor models. The process of obtaining base content, polymer, and oligomer parameters is illustrated, and for duplexes containing Watson-Crick pairs, fits to oligonucleotide duplex heat-of-formation data are shown to be statistically equivalent to existing models. © 2004 Wiley Periodicals, Inc.

Item Details

Item Type:Refereed Article
Research Division:Physical Sciences
Research Group:Other physical sciences
Research Field:Other physical sciences not elsewhere classified
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the physical sciences
UTAS Author:Bashford, JD (Dr James Bashford)
UTAS Author:Jarvis, PD (Dr Peter Jarvis)
ID Code:31315
Year Published:2004
Web of Science® Times Cited:1
Deposited By:Physics
Deposited On:2004-08-01
Last Modified:2005-06-22

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