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Accuracy, reproducibility and clinical utility of the CoaguChek S portable international normalized ratio monitor in an outpatient anticoagulation clinic
Citation
Jackson, SL and Bereznicki, LRE and Peterson, GM and Marsden, KA and Jupe, DML and Tegg, EM and Vial, JH and Kimber, R, Accuracy, reproducibility and clinical utility of the CoaguChek S portable international normalized ratio monitor in an outpatient anticoagulation clinic, Clinical and Laboratory Haematology, 26, (1) pp. 49-55. ISSN 0141-9854 (2004) [Refereed Article]
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Copyright Statement
The definitive published version is available online at: http://onlinelibrary.wiley.com/
Official URL: http://onlinelibrary.wiley.com/
DOI: doi:10.1111/j.0141-9854.2003.00578.x
Abstract
The accuracy and reproducibility of the CoaguChek S, and its clinical agreement with conventional laboratory international normalized ratio (INR) determination, were evaluated in an outpatient anticoagulation clinic setting. Forty-three patients provided 248 paired INR measurements for analysis. The paired results were highly correlated (r = 0.90). The mean coefficient of variation for the CoaguChek S for a random sample of 21 patients with three repeated tests each, was 4%. Clinical applicability was also measured by discrepant INR values, as defined in the literature by expanded and narrow agreement, and by INR values resulting in a different clinical decision by a blinded haematology registrar. Expanded agreement and narrow agreement between the two INR values occurred 90 and 88% of the time, respectively. The stricter criteria set down by the clinician resulted in 73% of paired results producing the same dosage decision. The CoaguChek S displayed good correlation with laboratory determination of INR and compared relatively well with expanded and narrow clinical agreement criteria.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | Warfarin;international normalized ratio;point-of-care;monitor;clinical agreement |
| Research Division: | Medical and Health Sciences |
| Research Group: | Public Health and Health Services |
| Research Field: | Health and Community Services |
| Objective Division: | Health |
| Objective Group: | Other Health |
| Objective Field: | Health not elsewhere classified |
| Author: | Jackson, SL (Dr Shane Jackson) |
| Author: | Bereznicki, LRE (Associate Professor Luke Bereznicki) |
| Author: | Peterson, GM (Professor Gregory Peterson) |
| Author: | Marsden, KA (Dr Katherine Marsden) |
| Author: | Tegg, EM (Dr Elizabeth Tegg) |
| Author: | Vial, JH (Associate Professor Janet Vial) |
| Author: | Kimber, R (Dr Roger Kimber) |
| ID Code: | 30004 |
| Year Published: | 2004 |
| Web of Science® Times Cited: | 17 |
| Deposited By: | Pharmacy |
| Deposited On: | 2004-08-01 |
| Last Modified: | 2012-03-14 |
| Downloads: | 0 |
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