Trevillian, L and Ponsonby, AL and Dwyer, T and Kemp, A and Cochrane, JA and Limm, LLY and Carmichael, A, Infant sleeping environment and asthma at 7 years: a prospective cohort study, American Journal of Public Health, 95, (12) pp. 2238-2245. ISSN 0090-0036 (2005) [Refereed Article]
Objectives: We investigated the role of infant bedding items, as part of a composite bedding environment, in the development of childhood wheezing.
Methods: This prospective cohort investigation involved 863 children who participated in an infant survey in 1988 and an asthma study in Tasmania, Australia, in 1995. The derived 3 composite infant bedding categories corresponded to increasing numbers of house dust mite (HDM)-rich bedding items used. Outcomes measured included recent and frequent wheezing.
Results: Composite infant bedding used was associated with recent wheezing. Effects increased at increasing levels of HDM-rich bedding items used. Effects were further enhanced by home environmental factors of bedroom heating, recent bedroom painting, and absence of bedroom carpeting. When any 2 or more of these environmental factors were present, a strong dose-response relationship was evident.
Conclusions: Our results show that bedding exposures in infancy are prospectively associated with childhood wheezing and that home environmental conditions may modify this association.
|Item Type:||Refereed Article|
|Research Division:||Health Sciences|
|Research Field:||Epidemiology not elsewhere classified|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Ponsonby, AL (Professor Anne Ponsonby)|
|UTAS Author:||Dwyer, T (Professor Terry Dwyer)|
|UTAS Author:||Cochrane, JA (Mrs Jennifer Cochrane)|
|UTAS Author:||Carmichael, A (Professor Allan Carmichael)|
|Web of Science® Times Cited:||17|
|Deposited By:||Menzies Centre|
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