eCite Digital Repository

Case-control study of lung cancer during 1994-1997 in the birth cohort in Tasmania, Australia, with an excess of female cases during 1983-1992

Citation

Blizzard, CL and Dwyer, T, Case-control study of lung cancer during 1994-1997 in the birth cohort in Tasmania, Australia, with an excess of female cases during 1983-1992, Cancer Causes and Control, 14, (2) pp. 123-129. ISSN 0957-5243 (2003) [Refereed Article]

DOI: doi:10.1023/A:1023001932619

Abstract

Objective: In Tasmania, Australia, lung cancer incidence for 25-44-year-old women has reached that of 25-44-year-old men despite less smoking by the women. We investigated whether this could be due to greater female-than-male relative risk for smoking. Methods: This was a case-control study of lung cancer in the 1939-1964 birth cohort. In person (n = 100) or by proxy, 158 of the 160 cases arising during 1994-1997 were interviewed. Controls were a representative sample of the cohort (response 82.8%). Detailed measurements of tobacco smoking were made by questionnaire, and using the results of 17 machine tests of cigarette "tar" yields. Results: The male smokers had greater accumulated exposure to smoking and, in reversal of the previously reported excess of female cases in this cohort, most (99/160) of the 1994-1997 cases were men. Nevertheless, the proportions attributable to smoking were similar: 0.86 (0.76-0.97) of male cases, and 0.87 (0.74-0.99) of female cases. Calculated relative to male never-smokers, the estimated relative risks were similar for male and female smokers, particularly with exposure measured by cumulative tar yield of all cigarettes smoked. Conclusions: We found no compelling evidence of greater susceptibility to lung cancer for female smokers.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cancer and Related Disorders
Author:Blizzard, CL (Associate Professor Leigh Blizzard)
Author:Dwyer, T (Professor Terry Dwyer)
ID Code:28385
Year Published:2003
Web of Science® Times Cited:4
Deposited By:Menzies Centre
Deposited On:2003-08-01
Last Modified:2007-05-29
Downloads:0

Repository Staff Only: item control page