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Modification of ion chromatographic separations by ionic and nonionic surfacants


Fritz, J and Yan, Z and Haddad, PR, Modification of ion chromatographic separations by ionic and nonionic surfacants, Journal of Chromatography A, 997, (1-2) pp. 21-31. ISSN 0021-9673 (2003) [Refereed Article]

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DOI: doi:10.1016/S0021-9673(03)00114-6


New findings are reported on simple ways to modify an ordinary HPLC column to obtain efficient ion chromatographic (IC) separations. Permanently coating a column with an ionic surfactant is known to produce an effective column for IC. We now show that incorporation of a nonionic surfactant in the coating, or coating in separate layers, results in a dramatic reduction of ion retention times and gives sharper peaks. Dynamic coating by incorporating a small amount of an alcohol, diol or zwitterion in the aqueous mobile phase permits good separations of alkanecarboxylic acids. A mobile phase containing a quaternary ammonium cation and a zwitterion anion provides excellent separations of common anions on a silica C18 column. An aqueous eluent containing a mixture of a zwitterion 4-(2-hydroxyethyl) acid and methanesulfonic acid can be used in conjunction with a standard cation exchange column. After passing through a membrane suppressor, the mobile phase has a slightly acidic pH, permitting divalent transition metal ions (as well as others) to be detected by conductivity.

Item Details

Item Type:Refereed Article
Keywords:Surfactants; Inorganic anions; Inorganic cations; Organic acids
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Fritz, J (Professor Jim Fritz)
UTAS Author:Yan, Z (Mr Zhu Yan)
UTAS Author:Haddad, PR (Professor Paul Haddad)
ID Code:27348
Year Published:2003
Web of Science® Times Cited:24
Deposited By:Chemistry
Deposited On:2003-08-01
Last Modified:2010-02-05

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