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Vacancy ion-exclusion chromatography of aromatic carboxylic acids on a weakly acidic cation-exchange resin

Citation

Helaleh, MIH and Tanaka, K and Mori, M and Xu, Q and Taoda, H and Ding, MY and Hu, W and Hasebe, K and Haddad, PR, Vacancy ion-exclusion chromatography of aromatic carboxylic acids on a weakly acidic cation-exchange resin, Journal Chromatography A, 997, (1-2) pp. 139-144. ISSN 0021-9673 (2003) [Refereed Article]

DOI: doi:10.1016/S0021-9673(03)00115-8

Abstract

Determination of aromatic carboxylic acids by conventional ion-exclusion chromatography is relatively difficult and methods generally rely on hydrophobic interaction between the solute and the resin. To overcome the difficulties in determining aromatic carboxylic acids a new approach is presented, termed vacancy ion-exclusion chromatography, which is based on use of the sample as mobile phase and an injection of aqueous 10% methanol onto a weakly acidic cation-exchange column (TSKgel OApak-A). Highly sensitive conductivity detection occurred with sharp and well-shaped peaks, leading to very efficient separations. The effects of sulfuric acid concentration added to the mobile phase, flow-rate, and column temperature on the retention volume of tested aromatic carboxylic acids was investigated. Retention times were found to be affected by the concentration of the analytes in the mobile phase and to some extent also by the addition of an organic modifier such as methanol to the injected water sample. Separation of sulfuric acid (SA), naphthalenetetracarboxylic acid (NTCA), phthalic acid (PA) and benzoic acid (BA) was satisfactory using this new approach. Detection limits were 0.66, 0.67, 0.42 and 0.86 μM and detector responses were linear in the range 1-100, 1-80, 2.5-100 and 10-40 μM, for SA, NTCA, PA and BA, respectively. Precision for retention times was 0.36% and for peak areas was 1.5%. © 2003 Elsevier Science B.V. All rights reserved.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Tanaka, K (Dr Kazuhiko Tanaka)
Author:Haddad, PR (Professor Paul Haddad)
ID Code:27346
Year Published:2003
Web of Science® Times Cited:16
Deposited By:Chemistry
Deposited On:2003-08-01
Last Modified:2011-10-12
Downloads:0

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