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Changes in the geographical and temporal patterns of cancer incidence among black gold miners working in South Africa, 1964-1996

Citation

McGlashan, ND and Harington, JS and Chelkowska, EZ, Changes in the geographical and temporal patterns of cancer incidence among black gold miners working in South Africa, 1964-1996, British Journal of Cancer, 88, (9) pp. 1361-1369. ISSN 0007-0920 (2003) [Refereed Article]

DOI: doi:10.1038/sj.bjc.6600841

Abstract

We describe here the results of the final 8 years of geographical and temporal data of a 33-year study of the cancer experience of 12.8 million man-years of black miners working on the gold fields of South Africa over the period 1964-96. These workers were recruited from 15 territories, the major areas during the most recent period being Lesotho (26.8%), Transkei (21.5%) and Mozambique (15%). The earliest analyses, 1964-71 and 1972-79, showed hepatocellular and oesophageal cancers to be the most frequent cancers. The final analysis, for 1989-96, however, shows marked temporal changes in the relative position of four cancers or grouped malignancies: respiratory cancer up by 236%, hepatocellular carcinoma down to 32%, oesophageal holding steady, and lymphatic system cancers up by 420%, almost certainly because of association with HIV/AIDS infection. Significant geographical variations occurring between the home areas of the miners are important, as mining operations have little to do with the cancers that develop. The causes are essentially socio-environmental rather than occupational, and this means that the rates of the major cancers in the miners are surrogate measures of the same cancers in the home areas. © 2003 Cancer Research UK.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Oncology and Carcinogenesis
Research Field:Oncology and Carcinogenesis not elsewhere classified
Objective Division:Health
Objective Group:Specific Population Health (excl. Indigenous Health)
Objective Field:Occupational Health
Author:McGlashan, ND (Dr Neil McGlashan)
Author:Chelkowska, EZ (Dr Elzbieta Chelkowska)
ID Code:27030
Year Published:2003
Web of Science® Times Cited:13
Deposited By:Mathematics
Deposited On:2003-08-01
Last Modified:2004-04-20
Downloads:0

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