eCite Digital Repository

Retinopathy of prematurity: recent advances in our understanding


Wheatley, C and Dickinson, JL and Mackey, DA and Craig, JE and Sale, MM, Retinopathy of prematurity: recent advances in our understanding, British Journal of Ophthalmology, 86, (6) pp. 696-701. ISSN 0007-1161 (2002) [Refereed Article]

DOI: doi:10.1136/bjo.86.6.696


Retinopathy of prematurity (ROP) has been recognised as an important cause of childhood visual impairment and blindness since the 1940s when improved facilities and treatment increased the survival rate of premature infants. Although its incidence and severity have been decreasing in developed countries over the past two decades, both are increasing in developing nations. ROP is consequently targeted as an important but avoidable disease. This review provides an updated summary and discussion of much of the work that has been produced through population, animal, cell culture, and genetic research. The authors examine the prevalence, risk factors, and possible causes of the disease with a particular focus on genetic studies. They conclude that while significant reductions in the disease have occurred in developed countries, further research is required to fully understand and prevent the disease. In the meantime, development and implementation of appropriate screening and treatment strategies will be critical in reducing blindness in developing countries.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Ophthalmology and optometry
Research Field:Ophthalmology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Wheatley, C (Ms Catherine Wheatley)
UTAS Author:Dickinson, JL (Professor Joanne Dickinson)
UTAS Author:Mackey, DA (Professor David Mackey)
UTAS Author:Craig, JE (Mr Jamie Craig)
UTAS Author:Sale, MM (Dr Michele Sale)
ID Code:24708
Year Published:2002
Web of Science® Times Cited:71
Deposited By:Menzies Centre
Deposited On:2002-08-01
Last Modified:2003-04-09

Repository Staff Only: item control page