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Quantifying the Change of Melanoma Incidence by Breslow Thickness


Qin, J and Berwick, M and Ashbolt, R and Dwyer, T, Quantifying the Change of Melanoma Incidence by Breslow Thickness, Biometrics, 58, (3) pp. 665-670. ISSN 0006-341X (2002) [Refereed Article]

DOI: doi:10.1111/j.0006-341X.2002.00665.x


Melanoma incidence has increased throughout the world over the past 25 years. A surrogate for the severity of melanoma is the Breslow thickness of the lesions. Data on melanoma, including Breslow thickness, were collected in 1978-1980 and 1988-1990 from the Tasmania Tumor Registry. We use a density ratio model to quantify the change of melanoma by Breslow thickness. In this model, the ratio of two densities is assumed to have a known form up to a parameter, but the underlying densities are not modeled. This model includes the length bias sampling model as a special case. The Kolmogorov-Smirnov test statistic is used to test the correctness of the density ratio model. Model-based cumulative distribution estimation is studied. Methodology developed in this article is applied to the Tasmania Tumor Registry data.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Oncology and carcinogenesis
Research Field:Oncology and carcinogenesis not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Ashbolt, R (Mrs Ashbolt)
UTAS Author:Dwyer, T (Professor Terry Dwyer)
ID Code:24651
Year Published:2002
Web of Science® Times Cited:27
Deposited By:Menzies Centre
Deposited On:2002-08-01
Last Modified:2003-04-07

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